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KMID : 0370220220660050225
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Yakhak Hoeji
2022 Volume.66 No. 5 p.225 ~ p.235
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Patterns of the Concurrent Use of Anti-dementia Drugs and Antipsychotics: Analysis using HIRA-APS-2018 Data
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Kim Hea-Lim
Lee Hye-Jae
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Abstract
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The number of dementia patients and the associated socio-economic burden are rapidly increasing in Korea.
Behavioral and psychological symptoms of dementia increase the burden on caregivers, thus primarily instigatingadmission to a nursing home. In this study, using 2018 Health Insurance Review and Assessment Service-Aged PatientSample (HIRA-APS) data, the pattern of concurrent use of anti-dementia and antipsychotic drugs by dementia patients wasinvestigated, and related factors were identified. The most frequently used combination were donepezil-quetiapine (52.8%),donepezil-memantine-quetiapine (13.8%), and donepezil-risperidone (8.8%). Logistic regression analysis revealed malepatients, those aged ≥75 years, medical aid beneficiaries, and those with Charlson Comorbidity Index (CCI) ≥5 to be morelikely to receive concomitant administration. The likelihood increased in patients visiting nursing or general hospitals, whileit decreased in patients visiting tertiary hospitals. Honam, Gyeongsang, and Chungcheong regions showed lower likelihoodof concurrent use than Seoul-metropolitan area. The results of this study provide basic evidence for further studies on theoutcome of concurrent use in dementia patients.
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KEYWORD
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Dementia, BPSD, Antipsychotics, HIRA-APS, Concurrent use
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